Antibiotics Linked to Type 2 Diabetes

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According to a new study, taking antibiotics on a regular basis could increase your chances of developing type 2 diabetes. Danish researchers investigated the link in a 2015 study published in the Journal of Clinical Endocrinology & Metabolism.

The researchers found that study participants who had taken more antibiotics leading up to the study were more likely to also be diagnosed with type 2 diabetes. “Patients with type 2 diabetes are overexposed to antibiotics compared with matched control persons without diabetes.” Surprisingly enough, overexposure to antibiotics as early as 15 years before the diabetes diagnosis was linked to an increased risk for diabetes.

However, the study does have a few limits. For example, the study did not prove if antibiotics caused the increased rate in diabetes, or if a person who was more likely to get diabetes was also more likely to use antibiotics. A direct cause-and-effect was not proven by this study. Still, the evidence is strong enough to warrant further research and to indicate that antibiotic use could lead to increased risk. We already know that using too many antibiotics can cause issues with beneficial bacteria in the gut, weight gain and sometimes even mood regulation.

Study details

The researchers examined the antibiotic prescriptions of over 170,000 Danes who had type 2 diabetes, and measured them against the prescription rates of nearly 1.3 million Danes who did not have diabetes. The researchers found that the individuals who were diagnosed with type 2 diabetes filled about 0.8 antibiotic prescriptions each year, while everyone else took out about 0.5 prescriptions each year. All study participants who had diabetes took out more antibiotic prescriptions.

Study participants who used antibiotics were about 50 percent more likely to get a diabetes diagnosis if they filled five or more antibiotic prescriptions in a year. Those who took out no prescriptions or one prescription were unlikely to be diagnosed with diabetes that year. The use of narrow-spectrum antibiotics were more likely to lead to an increased diabetes diagnosis than broad-spectrum antibiotics.

Antibiotics. Medical Concept with Blured Background.The study authors were not sure what caused the higher risk for diabetes with antibiotic use. The study authors theorized that diabetes can lower the immune system, possibly causing a greater need for antibiotics. Another theory suggested that repeated infections could increase the risk for developing diabetes.

Gut bacteria and diabetes

The researchers cited previous animal studies that show how antibiotics can damage beneficial gut bacteria, which work to digest and process sugar. The researchers theorized that the damage to these bacteria could be what is increasing diabetes risk by making the body work harder to process excess sugar.

Takeaway: avoid antibiotic use

This new study suggests that antibiotics could be responsible for an increase in type 2 diabetes risk. Previous studies have shown that excessive antibiotic use can damage beneficial bacteria in the intestines that are necessary for basic bodily systems and overall health. Too much antibiotic use can weaken the immune system and encourages the development of stronger bacteria that resist antibiotics.

The best way to lower your risk is to use antibiotics sparingly. Never take antibiotics for viral infections, and ask your doctor if there are alternatives you can take for common bacterial infections. Some natural remedies may be just as beneficial as antibiotics.

The Alternative Daily

Sources:
http://www.cbsnews.com/news/antibiotics-may-increase-type-2-diabetes-risk
http://press.endocrine.org/doi/abs/10.1210/jc.2015-2696

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