For decades, saturated fats have been lumped together as unhealthy. But new research is shining a light on C15:0 (pentadecanoic acid)—a unique odd-chain saturated fatty acid—showing it may actually be essential for long-term health.
Why It Matters
Studies published in journals such as Nature Communications and Scientific Reports suggest that higher C15:0 levels are linked to lower risks of heart disease, type 2 diabetes, and liver disorders. Research also points to anti-inflammatory and anti-aging benefits, thanks to C15:0’s ability to strengthen cell membranes, support mitochondria (the body’s energy factories), and regulate immunity. Unlike fragile polyunsaturated fats, C15:0 is highly stable, meaning it helps protect cells instead of making them vulnerable to oxidation.
Food Sources of C15:0
C15:0 is found in small amounts in certain whole foods, particularly:
- Whole-fat dairy: butter, whole milk, and cheese
- Fish: salmon, sardines, and other fatty fish
- Some plants: trace levels in certain seeds and legumes
Because the amounts in food are relatively small, researchers are exploring purified supplements as a consistent source.
How to Boost Intake Naturally
- Choose whole-fat dairy in moderation – Swap skim or fat-free options for full-fat milk, yogurt, or butter a few times per week.
- Eat fatty fish twice weekly – Not only does this supply C15:0, but it also delivers heart-healthy omega-3s.
- Balance, don’t overload – C15:0 works best as part of a diverse diet rich in whole foods, fruits, and vegetables.
The Bottom Line
C15:0 isn’t just another fat—it’s emerging as a pro-longevity nutrient that supports healthy aging, stronger immunity, and more resilient cells. While supplementation may become more common, simple food choices today can help you naturally add this promising “good fat” into your diet.