That evening glass of wine might feel harmless, but researchers from the University of Miami have a stark new warning: alcohol-related cancer deaths in the U.S. have doubled in just three decades.
In a nationwide analysis using data from the Global Burden of Disease database, scientists at the Sylvester Comprehensive Cancer Center uncovered a dramatic rise in alcohol-linked cancer fatalities—from 10,000 in 1990 to over 20,000 annually by 2021. Men over 55 were hit hardest, accounting for 75% of the increase.
But it’s not just older adults. “We’ve also seen an uptick in cancers among people under 50,” said Dr. Gilberto Lopes, medical oncologist and lead researcher. “In younger patients, alcohol appears to be a significant risk factor, especially for colorectal cancer.”
So, what makes alcohol so dangerous? Lopes explains that as the body breaks it down, alcohol produces toxic byproducts that can damage DNA and cause inflammation. For women, alcohol may disrupt hormone levels, raising the risk of breast cancer.
Earlier this year, the U.S. Surgeon General called for cancer warning labels on alcoholic drinks. And this new study only adds fuel to the fire.
But before you swear off sipping forever, Lopes encourages a balanced mindset. “We face cancer risks every day—pollution, radiation—but alcohol is one we can control,” he said. “Choosing to drink less, eat well, and stay active can make a measurable difference.”
The next step for researchers? Defining what, if any, amount of alcohol is actually “safe.” Until then, this study serves as a sobering reminder: cutting back could save more than just a headache tomorrow—it might save your life.